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Techniques of Solubilization of Drugs
Editor(s) :Samuel H. Yalkowsky

ISBN : 9789381075036
Name : Techniques of Solubilization of Drugs
Price : 1995.00
Editor/s : Samuel H. Yalkowsky
Type : Reference Book
Pages : 224
Year of Publication : 2011
Publisher : PharmaMed Press/BSP Books
Binding : Hardback

About the Book

This book was developed in an attempt to provide a comprehensive guide to the techniques available for solubilizing drugs in aqueous vehicles. Since surfactant solubilization is extremely important in pharmaceutical systems and is by far the most studied of the techniques covered, it is discussed in the greatest detail in the book.

            Solubilization by cosolvents, complexing agents, crystal modification, and prodrug formation can individually or in combination be an extremely valuable means of solubilizing drugs. Each of these techniques is discussed from both the theoretical and practical points of view.

Salient Features

 For each technique, a wide variety of examples is provided along with rational guidelines for application to new and unstudied drugs

      To aid the pharmaceutical scientist in understanding, selecting, and utilizing all of the available means of overcoming solubility problems. 

Contents

1. Solubility and Solubilization of Nonelectrolytes

2. Drug Solubilization in Surfactant Systems

3. Solubilization of Drugs by cosolvents

4. Alteration of Apparent Solubility through Complexation

5. Solubilization by Solid-State Manipulation

6. Drug Derivation as a means of Solubilization: Physicochemical and Biochemical strategies

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