About the Book:
Development of Vaccines: sets forth the issues and the challenges of vaccine development and the solutions needed to seamlessly advance a biologic drug formulation from discovery through al the essential steps that lead to a successful clinical vaccine trial. the authors skillfully guide you through everything you need to know, including current analytical tools and techniques, vaccine expression, purification, formulation, and preclinical testing, Not only does the book guide you through lab work, it also explaigulatory submissions process, helping you gather and report the necessary data.
Divided into five sections, this book serves as a reference to all the critical steps that take place form discovery to clinical trials:
· Details all the tools needed for immunogen design and development
· Investigates vaccine platforms, including virus-like particles, nanocapsules, DNA Vaccines, and protein expression and purification
· Explains the spectroscopy and biophysics techniques needed or accurate immunogen charcterization
· Demonstrates how to optimize formulations and evaluate stability
· Details all the steps needed to file a new application for clinical vaccine testing
Contents:
Part 1: Immunogen Design
Part 2: Vaccine Platforms
Part 3: Characterization of Immunogens
Part 4: Formulation Optimization And Stability Evaluation
About the Editors:
Manmohan Singh, PhD, is currently working as the Global Head of Vaccine Formulation Science at Novartis Vaccines and Diagnostics in Cambridge, Massachusetts. Dr. Singh is a well-known expert in the areas of vaccine formulations and adjuvant research and has been working in vaccine R&D for the last twenty years. He has authored over 100 peer-reviewed manuscripts, review articles, and book chapters in this area. Dr. Singh is on the editorial board of seven international journals and has contributed to organizing several international vaccine conferences. He is also the editor of Vaccine Adjuvants and Delivery Systems (also published by Wiley).
